Drug Reference
Cardiac
Aspirin
Antiplatelet (COX inhibitor)
IndicationAdult
ACSAdult162–325 mg chewed (non-enteric coated), then 81 mg daily
Indications
- Suspected ACS
- Acute ischemic stroke (after lytic window / 24 h after lytics)
Contraindications & cautions
- True aspirin allergy
- Active GI bleeding
Key pearls
- Reduces mortality in STEMI comparable to fibrinolysis
- Rectal 300 mg if unable to swallow