Drug Reference
Antidotes
Calcium chloride
Electrolyte (10% = 100 mg/mL; 27.2 mg/mL elemental Ca)
IndicationAdultPediatric
StandardAdult1 g (10 mL of 10%) IV over 2–5 min (push in arrest)Peds20 mg/kg (0.2 mL/kg)
Indications
- Hyperkalemia with ECG changes
- Calcium channel blocker / β-blocker overdose
- Hypermagnesemia
- Hypocalcemia (massive transfusion)
Contraindications & cautions
- Digoxin toxicity (relative; historical concern)
- Hypercalcemia
Key pearls
- 3× the elemental calcium of gluconate
- Central line preferred: severe tissue necrosis if extravasated
- Never through the same line as bicarbonate