Drug Reference
Other
Hydrocortisone
Corticosteroid (glucocorticoid + mineralocorticoid)
IndicationAdultPediatric
Septic shockAdult50 mg IV every 6 h (200 mg/day)Peds-
Adrenal crisisAdult100 mg IV, then 50 mg every 6 hPeds2 mg/kg (max 100 mg)
Indications
- Septic shock requiring ongoing vasopressors
- Adrenal crisis
- Anaphylaxis adjunct
Contraindications & cautions
- Systemic fungal infection (relative)
Key pearls
- Hyperglycemia and hypernatremia
- Steroids act in hours, not minutes