Drug Reference
Pressors
Isoproterenol
Pure β₁/β₂ agonist
IndicationAdultPediatric
InfusionAdult2–10 mcg/min, titrate to HRPeds0.05–2 mcg/kg/min
Indications
- Torsades from bradycardia (pause-dependent) as overdrive
- Bradycardia in heart transplant
- Brugada electrical storm
Contraindications & cautions
- Congenital long QT (adrenergic-dependent)
- Digitalis toxicity
- Active ischemia
Key pearls
- Increases myocardial O₂ demand; can drop BP (β₂ vasodilation)